Services
Custom Synthesis
• Heterocyclic Compounds
• Chiral Compounds
• Peptide Synthesis
• Nucleosides & Nucleotides
• Carbohydrate Chemistry
• Oligonucleotides
• PROTAC Compounds
• ADC Linker
• Lipids in Drug Discovery
• API Reference standard,
Impurities & Metabolites
• Agro Reference Standard,
Impurities & Metabolites
• Material Science related
chemicals/OLED/Performance
Chemicals
IRA BIOSCIENCES offers a tailor-made custom synthesis service to meet our customer objectives using existing literature protocols or design and development of new, efficient synthetic routes to accomplish target molecules at a faster phase. Our service segment offers comprehensive support ranging from milligrams to multi-kilograms under a “Fee for Service” (FFS) business model. We specialize in custom synthesis, particularly focusing on complex chemistry molecules that are ground-breaking and notoriously challenging to produce. Our synthesis capabilities extend to a wide array of chemistry molecules, even those fraught with complexities and issues. With our versatile experienced, good problem-solving team, we excel at handling the most demanding chemistry challenges and delivering the Customer expectations. IRA Biosciences provide excellent service through a cutting-edge tools like high-throughput Catalyst screening, Photo-Redox Chemistry, Microwave chemistry, Electrochemistry
Data-Driven Approach:
Once the target compounds are synthesized, we provide clients with detailed data, primarily consisting of LCMS, 1H NMR, solubility, melting point (MP), and Optical Rotation (SOR).
Discovery Chemistry
• Hit Identification
• Hit-to-Lead Optimization
• Computational Chemistry
Support
• Target Validation and
Chemical Biology
• Collaborative Research
Models
IRA BIOSCIENCES provides high-quality medicinal chemistry services that efficiently progress drug discovery projects from Hit identification through Lead generation and optimization. Our medicinal chemists have extensive experience against a broad range of target types. After the designing of Library Compounds, we execute the synthesis using parallel synthesis tool to generate analogs in a quick mode We work closely with our partners to design and synthesize compounds for their targets and assays, leading ultimately to the identification of developed candidates.
IRA BIOSCIENCES focus;
We design of route and synthesis support for the “Novel Chemistry Targets” under the CDA and MSA as focused libraries / different scaffolds of desired skeleton to support NCE. The synthesis of multi-step complex chemistry molecules at mg scale to grams scale for “customer to check for quick metabolic stability” and bioactivities of required lead molecules. The targets under these FTE service will be made very swiftly to support clients “NCE/ NDDS projects” We support all difficult to perform / rare to make chemistry molecules under this category of service. We deliver chemistry targets much faster with >95% LCMS and clean HNMR data
Peptide Synthesis
• Custom Peptide Synthesis
• Modified Peptides
• High-Purity Peptides
• Peptide Libraries
Peptide research gained unprecedented growth for a broad range of applications in medicine, biotechnology, chemical biology, and therapeutic research.
The prospects for peptide research and development are very encouraging. The marketing approvals for peptide drugs increasing year by year, over 60 peptide drugs approved by North America, Europe, and the Asia Pacific markets, and more than 150 peptides in active clinical trials. The increased demand for peptide therapeutics, the global market is projected to grow from USD 42.1 billion in 2024 to USD 117.4 billion by 2034.
Our Custom Peptide Services:
IRA BIOSCIENCES has expertise in both, liquid-phase (LPPS) and solid-phase peptide synthesis (SPPS), which allows us to deliver numerous peptides for therapeutic and diagnostic applications.
We specialize in the synthesis of high-quality peptides at a competitive price. We offer a wide range of peptide synthesis services for API peptides, cosmetic peptides, and library of custom peptides with the purity ranging from research grade to commercial grade.
Process Development
• Route Scouting and
Development
• Chemical Process
Optimization
• Computational Chemistry
Support
• Target Validation and
Chemical Biology
• Collaborative Research
Models
The bulk manufacturing is undergoing rapid expansions due to unmet needs in access to API and API intermediates. Also, raising concerns about bulk manufacturing due to the lack of innovations for minimizing effluent. IRA BIOSCIENCES committed to developing robust, cost-effective, scalable and non-hazardous processes for the manufacturing of APIs, API intermediates including key starting materials, Agri products, and specialty chemicals to bring value to our customers with minimal environmental effect.
Under This category – We offer the quick & Rigorous literature survey and patent evaluation and workout on all possible route of synthesis finalize the synthetic plan with customer.
We perform process development – Optimization and freezing on process to ensure that we can take consistent lab scale batches and then move forward to Pilot scale batches as well.
Once the multigram scale process is set and checked on repeated on Kg scale then based on the required quantity we go for manufacturing campaign (Technical Package).
Generation of technical documents to fulfil the customer requirement
We offer kg to multi kg scale very quickly. The fast synthesis with reliable quality is the essence of all our chemistry services.
Reference Standard, Metabolite & impurities (Pharma & Agro)
• IRA BIOSCIENCES offers a broad
spectrum of reference standards
for APIs, impurities, and
metabolites according to the
regulatory requirements